Browsing Centre for Microvascular Research (CMR) by Author "El-Mansi, S"
Now showing items 1-3 of 3
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Emerging mechanisms to modulate VWF release from endothelial cells
El-Mansi, S; Nightingale, TD (2021) -
Myosin-1C augments secretion of von Willebrand factor by linking contractile actomyosin machinery to the plasma membrane.
El-Mansi, S; Mitchell, TP; Mobyen, G; McKinnon, TA; Miklavc, P; Frick, M; Nightingale, TD (American Society of Hematology (ASH Publications), 2024-04-26)Blood endothelial cells control the hemostatic and inflammatory response by secreting von Willebrand factor (VWF) and P-selectin from storage organelles called Weibel-Palade bodies (WPB). Actin-associated motor proteins ... -
Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor
El-Mansi, S; Robinson, CL; Kostelnik, KB; McCormack, JJ; Mitchell, TP; Lobato-Marquez, D; Rajeeve, V; Cutillas, P; Cutler, DF; Mostowy, S (2023)