Browsing Centre for Biochemical Pharmacology by Subject "pancreatic cancer"
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Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors
(MDPI, 2020-12-18)Pancreatic cancer (PC) is one of the most aggressive cancers in the world. Several extracellular factors are involved in its development and metastasis to distant organs. In PC, the protein Annexin A1 (ANXA1) appears to ... -
Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component.
(EMBO Press, 2021-05-25)Pancreatic ductal adenocarcinoma (PDAC) patients frequently suffer from undetected micro-metastatic disease. This clinical situation would greatly benefit from additional investigation. Therefore, we set out to identify ...