Browsing Centre for Biochemical Pharmacology by Subject "Leucine"

Now showing items 1-1 of 1

    • Structural basis for a complex I mutation that blocks pathological ROS production. 

      Yin, Z; Burger, N; Kula-Alwar, D; Aksentijević, D; Bridges, HR; Prag, HA; Grba, DN; Viscomi, C; James, AM; Mottahedin, A (2021-01-29)
      Mitochondrial complex I is central to the pathological reactive oxygen species (ROS) production that underlies cardiac ischemia-reperfusion (IR) injury. ND6-P25L mice are homoplasmic for a disease-causing mtDNA point ...