Browsing Centre for Biochemical Pharmacology by Subject "Immunotherapy"
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Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency.
(2021-08-10)Nox2 is a ROS-generating enzyme, deficiency of which increases suppression by Tregs in vitro and in an in vivo model of cardiac remodelling. Since Tregs have emerged as a candidate therapy in autoimmunity and transplantation, ...