Browsing Centre for Biochemical Pharmacology by Author "Tungen, JE"
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Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA.
Tungen, JE; Gerstmann, L; Vik, A; De Matteis, R; Colas, RA; Dalli, J; Chiang, N; Serhan, CN; Kalesse, M; Hansen, TV (2018-12-04)New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, that is, the resolvins, are excellent candidates displaying ... -
Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA.
Primdahl, KG; Tungen, JE; De Souza, PRS; Colas, RA; Dalli, J; Hansen, TV; Vik, A (2017-10-18)PD1n-3 DPA is a specialized pro-resolving lipid mediator that displays potent anti-inflammatory properties and pro-resolving bioactivities. Such naturally occurring compounds are of current interest in biomolecular chemistry ... -
Stereoselective synthesis of MaR2(n-3) (DPA)
Sonderskov, J; Tungen, JE; Palmas, F; Dalli, J; Serhan, CN; Stenstrom, Y; Hansen, TV (2020-02-13)