Browsing Centre for Biochemical Pharmacology by Author "Pinto, AL"
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Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
Oggero, S; de Gaetano, M; Marcone, S; Fitzsimons, S; Pinto, AL; Ikramova, D; Barry, M; Burke, D; Montero-Melendez, T; Cooper, D (Wiley, 2021-04-27)Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF-α display ... -
β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis.
Hussain, MT; Austin-Williams, S; Wright, TD; Dhawan, UK; Pinto, AL; Cooper, D; Norling, LV (MDPI, 2024-04-26)Osteoarthritis (OA) is the most prevalent age-related degenerative disorder, which severely reduces the quality of life of those affected. Whilst management strategies exist, no cures are currently available. Virtually all ...