Browsing Centre for Biochemical Pharmacology by Author "O'Brien, BA"
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Intracellular sodium elevation reprograms cardiac metabolism.
Aksentijević, D; Karlstaedt, A; Basalay, MV; O'Brien, BA; Sanchez-Tatay, D; Eminaga, S; Thakker, A; Tennant, DA; Fuller, W; Eykyn, TR (2020-08-28)Intracellular Na elevation in the heart is a hallmark of pathologies where both acute and chronic metabolic remodelling occurs. Here, we assess whether acute (75 μM ouabain 100 nM blebbistatin) or chronic myocardial Nai ... -
Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?
Aksentijevic, D; O'Brien, BA; Eykyn, TR; Shattock, MJ (2018)