Browsing Centre for Biochemical Pharmacology by Author "O'Brien, A"
Now showing items 1-3 of 3
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Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease.
China, L; Maini, A; Skene, SS; Shabir, Z; Sylvestre, Y; Colas, RA; Ly, L; Becares Salles, N; Belloti, V; Dalli, J (2018-05)BACKGROUND & AIMS: Patients with acute decompensation and acute-on-chronic liver failure (AD/ACLF) have immune dysfunction, which increases their risk for infections; however, there are no effective treatments to restore ... -
Immune Regulatory Mediators in Plasma from Patients with Acute Decompensation are Associated With 3-month Mortality.
Becares, N; Härmälä, S; China, L; Colas, RA; Maini, AA; Bennet, K; Skene, SS; Shabir, Z; Dalli, J; O'Brien, A (2019-08-22)BACKGROUND & AIMS: Infection is a common cause of death in patients with cirrhosis. We investigated the association between the innate immune response and death within 3 months of hospitalization. METHODS: Plasma samples ... -
Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities
China, L; Maini, A; Colas, R; Ly, L; Dalli, J; Gilroy, D; O'Brien, A; Infection, ATTIREAP (2017)