Browsing Centre for Biochemical Pharmacology by Author "Lechler, RI"
Now showing items 1-3 of 3
-
Evaluation of Competing Methodologies for In Vivo Tracking of Human Regulatory T Cells Intended for Adoptive Cell Therapy in Transplantation
Jacob, J; Nadkarni, S; Volpe, A; Peng, Q; Tung, S; Hannen, R; Scotta, C; Lechler, RI; Marelli-Berg, F; Smyth, L (2021-04-27)Meeting Abstract 792 from ASGCT Annual Meeting Abstracts -
Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency.
Trevelin, SC; Zampetaki, A; Sawyer, G; Ivetic, A; Brewer, AC; Smyth, LA; Marelli-Berg, F; Köchl, R; Lechler, RI; Shah, AM (2021-08-10)Nox2 is a ROS-generating enzyme, deficiency of which increases suppression by Tregs in vitro and in an in vivo model of cardiac remodelling. Since Tregs have emerged as a candidate therapy in autoimmunity and transplantation, ... -
Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment
Jacob, J; Nadkarni, S; Volpe, A; Peng, Q; Tung, SL; Hannen, RF; Mohseni, YR; Scotta, C; Marelli-Berg, FM; Lechler, RI (2021-03-12)