Browsing Centre for Biochemical Pharmacology by Author "Jackson, DJ"
Now showing items 1-15 of 15
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Association between pre-biologic T2-Biomaker combinations and response to biologics in patients with severe asthma
Porsbjerg, CM; Townend, J; Bergeron, C; Christoff, GC; Katsoulotos, GP; Larenas-Linnemann, D; Tran, TN; Al-Lehebi, R; Bosnic-Anticevich, SZ; Busby, J -
Association Between T2-related Comorbidities and Effectiveness of Biologics in Severe Asthma.
Wechsler, ME; Scelo, G; Larenas-Linnemann, DES; Torres-Duque, CA; Maspero, J; Tran, TN; Murray, RB; Martin, N; Menzies-Gow, AN; Hew, M (2023-11-28)RATIONALE: Previous studies investigating comorbidity impact on biologic effectiveness have been relatively small, of short duration, and have not compared biologic classes. OBJECTIVES: To determine the association between ... -
Benralizumab Effectiveness in Severe Asthma Is Independent of Previous Biologic Use
Jackson, DJ; Burhan, H; Menzies-Gow, A; Pfeffer, P; Nanzer, A; Gil, EG; Morris, T; Tran, TN; Hirsch, I; Dube, S (2022) -
Characterisation of patients with severe asthma in the UK Severe Asthma Registry in the biologic era.
Jackson, DJ; Busby, J; Pfeffer, PE; Menzies-Gow, A; Brown, T; Gore, R; Doherty, M; Mansur, AH; Message, S; Niven, R (BMJ, 2020-12-09)BACKGROUND: The UK Severe Asthma Registry (UKSAR) is the world's largest national severe asthma registry collecting standardised data on referrals to UK specialist services. Novel biologic therapies have transformed the ... -
CHARACTERISTICS OF PATIENTS IN THE UK SEVERE ASTHMA REGISTRY: VARIATION BY ETHNICITY
Busby, J; Jackson, DJ; Mansur, AH; Menzies-Gow, A; Heaney, LG; Chaudhuri, R; Pfeffer, PE (2019-11-12)Abstract P152 from British Thoracic Society Winter Meeting 2019, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 4 to 6 December 2019 -
Clinical Effectiveness of Benralizumab Is Independent of Baseline FeNO in Severe Eosinophilic Asthma: A Retrospective Real-World Observation Study in Five UK Severe Asthma Centers
Jackson, DJ; Burhan, H; Menzies-Gow, A; Pfeffer, PE; Nanzer, A; Gil, EG; Morris, T; Tran, TN; Hirsch, I; Dube, S (2021-05-01) -
Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both
Pfeffer, PE; Ali, N; Murray, R; Ulrik., C; Tran, TN; Maspero, J; Peters, M; Christoff, GC; Sadatsafavi, M; Torres-Duque, CA (2023) -
Eosinophilic and non-eosinophilic asthma: an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort.
Heaney, LG; Perez de Llano, L; Al-Ahmad, M; Backer, V; Busby, J; Canonica, GW; Christoff, GC; Cosio, BG; FitzGerald, JM; Heffler, E (2021-04-19)BACKGROUND: Phenotypic characteristics of eosinophilic and non-eosinophilic asthma patients are not well-characterized in global, real life severe asthma cohorts. RESEARCH QUESTION: What is the prevalence of eosinophilic ... -
Ethnic differences in severe asthma clinical care and outcomes: an analysis of United Kingdom primary and specialist care.
Busby, J; Heaney, L; Brown, T; Chaudhuri, R; Dennison, P; Gore, R; Jackson, DJ; Mansur, A; Menzies-Gow, A; Message, S -
Factors associated with frequent exacerbations in the UK Severe Asthma Registry.
Yang, F; Busby, J; Heaney, LG; Menzies-Gow, A; Pfeffer, PE; Jackson, DJ; Mansur, AH; Siddiqui, S; Brightling, CE; Niven, R (Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology, 2021-01-15)BACKGROUND: Frequent exacerbations are an important cause of morbidity in patients with severe asthma. OBJECTIVE: Our aim was to identify factors associated with frequent exacerbations in a large well-characterized severe ... -
Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry.
Chen, W; Tran, TN; Sadatsafavi, M; Murray, R; Wong, NCB; Ali, N; Ariti, C; Bulathsinhala, L; Gil, EG; FitzGerald, JM (2023-09)BACKGROUND: Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. OBJECTIVE: To examine the ... -
The impact of the first COVID-19 surge on severe asthma patients in the UK. Which is worse: the virus or the lockdown?
Smith, SJ; Busby, J; Heaney, LG; Pfeffer, PE; Jackson, DJ; Yang, F; Fowler, SJ; Menzies-Gow, A; Idris, E; Brown, T (2021-01)Asthma therapy, including monoclonal antibodies, was not associated with #COVID19 infection or hospitalisation in a UK severe asthma population. Shielding led to a reported worsening of mental health in nearly half of ... -
International severe asthma registry (ISAR): protocol for a global registry
FitzGerald, JM; Tran, TN; Alacqua, M; Altraja, A; Backer, V; Bjermer, L; Bjornsdottir, U; Bourdin, A; Brusselle, G; Bulathsinhala, L (BioMed Central, 2020-08-14) -
Reply to "Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry".
Chen, W; Tran, TN; Sadatsafavi, M; Murray, RB; Boon Wong, NC; Ali, N; Ariti, C; Bulathsinhala, L; Garcia Gil, E; FitzGerald, JM (2024-02) -
USE OF A CONNECTED INHALER SYSTEM IN THE PRE-BIOLOGIC ASSESSMENT OF PATIENTS WITH SEVERE ASTHMA
Holmes, J; Dennison, P; Jackson, DJ; D'Ancona, G; Mansur, A; Menzies-Gow, A; Patel, P; Pfeffer, P; Chen, C; Shaw, D (2021)