Browsing Centre for Biochemical Pharmacology by Author "Iqbal, A"

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    • The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing 

      Fu, H; Vuononvirta, J; Fanti, S; Bonacina, F; D’Amati, A; Wang, G; Poobalasingam, T; Fankhaenel, M; Lucchesi, D; Coleby, R (Nature Research, 2023)
      T cell activation is associated with a profound and rapid metabolic response to meet increased energy demands for cell division, differentiation and development of effector function. Glucose uptake and engagement of the ...

    • A pro-resolving role for Galectin-1 in acute inflammation 

      Norling, L; Cooper, D; Law, H; Wright, R; Iqbal, A (Frontiers Media, 2020-03-20)
      Galectin-1 (Gal-1) exerts immune-regulatory and anti-inflammatory actions in animal models of acute and chronic inflammation. Its release into the extracellular milieu often correlates with the peak of inflammation suggesting ...