Browsing Centre for Biochemical Pharmacology by Author "Hansen, TV"
Now showing items 1-11 of 11
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Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction.
Fosshaug, LE; Colas, RA; Anstensrud, AK; Gregersen, I; Nymo, S; Sagen, EL; Michelsen, A; Vinge, LE; Øie, E; Gullestad, L (2019-08)BACKGROUND: Termination of acute inflammation is an active process orchestrated by lipid mediators (LM) derived from polyunsaturated fatty acids, referred to as specialized pro-resolving mediators (SPM). These mediators ... -
Enzymatic studies with 3-oxa n-3 DPA.
Pangopoulos, MK; Nolsøe, JMN; Antonsen, SG; Colas, RA; Dalli, J; Aursnes, M; Stenstrøm, Y; Hansen, TV (Elsevier, 2020-02-08)Cyclooxygenase-2 and several lipoxygenases convert polyunsaturated fatty acids into a large variety of products. During inflammatory processes, these enzymes form several distinct families of specialized pro-resolving lipid ... -
The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions.
Hansen, TV; Dalli, J; Serhan, CN (2017-11)Resolvins, protectins and maresins are individual families of specialized pro-resolving mediators biosynthesized from the dietary n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. These ... -
PCn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function
Pistorius, K; Souza, PR; De Matteis, R; Austin-Williams, S; Primdahl, KG; Vik, A; Mazzacuva, F; Colas, RA; Marques, RM; Hansen, TV (2018-06-21) -
Protectin D1(n-3 DPA) and resolvin D5(n-3 DPA) are effectors of intestinal protection
Gobbetti, T; Dalli, J; Colas, RA; Canova, DF; Aursnes, M; Bonnet, D; Alric, L; Vergnolle, N; Deraison, C; Hansen, TV (2017-04-11) -
Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid
Vik, A; Dalli, J; Hansen, TV (2017-06-01) -
Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA.
Tungen, JE; Gerstmann, L; Vik, A; De Matteis, R; Colas, RA; Dalli, J; Chiang, N; Serhan, CN; Kalesse, M; Hansen, TV (2018-12-04)New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, that is, the resolvins, are excellent candidates displaying ... -
Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA.
Primdahl, KG; Tungen, JE; De Souza, PRS; Colas, RA; Dalli, J; Hansen, TV; Vik, A (2017-10-18)PD1n-3 DPA is a specialized pro-resolving lipid mediator that displays potent anti-inflammatory properties and pro-resolving bioactivities. Such naturally occurring compounds are of current interest in biomolecular chemistry ... -
Stereoselective synthesis of MaR2(n-3) (DPA)
Sonderskov, J; Tungen, JE; Palmas, F; Dalli, J; Serhan, CN; Stenstrom, Y; Hansen, TV (2020-02-13) -
Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2(n-3 DPA)
Reinertsen, AF; Primdahl, KG; De Matteis, R; Dalli, J; Hansen, TV (2022) -
Synthesis of 13 (R)-Hyd roxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins
Primdahl, KG; Aursnes, M; Walker, ME; Colas, RA; Serhan, CN; Dalli, J; Hansen, TV; Vik, A (2016-10)