Browsing Centre for Biochemical Pharmacology by Author "Godson, C"
Now showing items 1-4 of 4
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Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms)
de Gaetano, M; Tighe, C; Gahan, K; Zanetti, A; Chen, J; Newson, J; Cacace, A; Marai, M; Gaffney, A; Brennan, E (American Chemical Society, 2021-06-17)Failure to resolve inflammation underlies many prevalent pathologies. Recent insights have identified lipid mediators, typified by lipoxins (LXs), as drivers of inflammation resolution, suggesting potential therapeutic ... -
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
Oggero, S; de Gaetano, M; Marcone, S; Fitzsimons, S; Pinto, AL; Ikramova, D; Barry, M; Burke, D; Montero-Melendez, T; Cooper, D (Wiley, 2021-04-27)Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF-α display ... -
Formyl peptide receptor type 2 agonists to kick-start resolution pharmacology
Perretti, M; Godson, C (2020-10) -
Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35
Qin, CX; Norling, LV; Vecchio, EA; Brennan, EP; May, LT; Wootten, D; Godson, C; Perretti, M; Ritchie, RH (2022)