Browsing Centre for Biochemical Pharmacology by Author "Belvedere, R"
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Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors
Novizio, N; Belvedere, R; Pessolano, E; Tosco, A; Porta, A; Perretti, M; Campiglia, P; Filippelli, A; Petrella, A (MDPI, 2020-12-18)Pancreatic cancer (PC) is one of the most aggressive cancers in the world. Several extracellular factors are involved in its development and metastasis to distant organs. In PC, the protein Annexin A1 (ANXA1) appears to ... -
Mesoglycan connects Syndecan-4 and VEGFR2 through Annexin A1 and formyl peptide receptors to promote angiogenesis in vitro.
Pessolano, E; Belvedere, R; Novizio, N; Filippelli, A; Perretti, M; Whiteford, J; Petrella, A (2021-05-31)Mesoglycan is a mixture of glycosaminoglycans (GAG) with fibrinolytic effects and the potential to enhance skin wound repair. Here, we have used endothelial cells isolated from Wild Type (WT) and Syndecan-4 null (Sdc4-/-) ...