Browsing Centre for Biochemical Pharmacology by Title
Now showing items 323-333 of 333
-
Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS.
(1999)This study compares the signal transduction pathway which leads to the upregulation of intercellular adhesion molecule-1 (ICAM-1) expression with that of the increase in the expression of inducible nitric oxide synthase ... -
Utility of Immunology, Microbiology and Helminth Investigations in Clinical Assessment of Severe Asthma.
(2020-12-23)Objective: Systematic assessment of patients with potential severe asthma is key to identification of treatable traits and optimal management. Assessment of anti-microbial immune function is part of that assessment at many ... -
Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets.
(2018-03-06)Visceral adipose tissue (VAT) has multiple roles in orchestrating whole-body energy homeostasis. In addition, VAT is now considered an immune site harboring an array of innate and adaptive immune cells with a direct role ... -
Vitamin D Counteracts an IL-23-Dependent IL-17A+IFN-γ+ Response Driven by Urban Particulate Matter.
(American Thoracic Society, 2017-09-01)Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL-17A, which UPM is reported to promote. ... -
Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial
(Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology., 2017-05-26) -
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure.
(2021-08-06)Elevated intracellular Na (Nai) and metabolic impairment are interrelated pathophysiological features of the failing heart (HF). There have been a number of studies showing that myocardial sodium elevation subtly affects ... -
β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis.
(MDPI, 2024-04-26)Osteoarthritis (OA) is the most prevalent age-related degenerative disorder, which severely reduces the quality of life of those affected. Whilst management strategies exist, no cures are currently available. Virtually all ...