Browsing Centre for Biochemical Pharmacology by Title
Now showing items 108-127 of 333
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Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
(Wiley, 2021-04-27)Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF-α display ... -
Factors associated with frequent exacerbations in the UK Severe Asthma Registry.
(Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology, 2021-01-15)BACKGROUND: Frequent exacerbations are an important cause of morbidity in patients with severe asthma. OBJECTIVE: Our aim was to identify factors associated with frequent exacerbations in a large well-characterized severe ... -
Feasibility of real-time capture of routine clinical data in the electronic health record: a hospital-based, observational service-evaluation study.
(2018-03-08)OBJECTIVES: The electronic health record (EHR) is underused in the hospital setting. The aim of this service evaluation study was to respond to National Health Service (NHS) Digital's ambition for a paperless NHS by capturing ... -
Findings of Impaired Hearing in Patients With Nonfluent/Agrammatic Variant Primary Progressive Aphasia.
(American Medical Association, 2019-02-11)Importance: Despite being characterized as a disorder of language production, nonfluent/agrammatic variant primary progressive aphasia (nfvPPA) is frequently associated with auditory symptoms. However, to our knowledge, ... -
From Welfare to Warfare: The Arbitration of Host-Microbiota Interplay by the Type VI Secretion System.
(Frontiers Media, 2020)The health of mammals depends on a complex interplay with their microbial ecosystems. Compartments exposed to external environments such as the mucosal surfaces of the gastrointestinal tract accommodate the gut microbiota, ... -
The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing
(Nature Research, 2023)T cell activation is associated with a profound and rapid metabolic response to meet increased energy demands for cell division, differentiation and development of effector function. Glucose uptake and engagement of the ...