Browsing Wolfson Institute of Preventive Medicine by Author "Noyce, AJ"
Now showing items 1-20 of 76
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Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
Lubbe, SJ; Escott-Price, V; Gibbs, JR; Nalls, MA; Bras, J; Price, TR; Nicolas, A; Jansen, IE; Mok, KY; Pittman, AMOligogenic inheritance implies a role for several genetic factors in disease etiology. We studied oligogenic inheritance in Parkinson’s (PD) by assessing the potential burden of additional rare variants in established ... -
Application of a Simple Parkinson's Disease Risk Score in a Longitudinal Population-Based Cohort.
Marini, K; Mahlknecht, P; Tutzer, F; Stockner, H; Gasperi, A; Djamshidian, A; Willeit, P; Kiechl, S; Willeit, J; Rungger, G (2020-06-03)BACKGROUND: Identifying individuals at risk of developing Parkinson's disease (PD) is critical to define target populations for future neuroprotective trials. OBJECTIVE: The objective of this study was to apply the PREDICT-PD ... -
Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population
Simonet, C; Bestwick, J; Jitlal, M; Waters, S; Ben-Joseph, A; Marshall, CR; Dobson, R; Marrium, S; Robson, J; Jacobs, BM (2022) -
Association Between Antiepileptic Drugs and Incident Parkinson Disease in the UK Biobank
Belete, D; Jacobs, BM; Simonet, C; Bestwick, JP; Waters, S; Marshall, CR; Dobson, R; Noyce, AJ (2023) -
Big data, machine learning and artificial intelligence: a neurologist's guide.
Auger, SD; Jacobs, BM; Dobson, R; Marshall, CR; Noyce, AJ (2020-09-29)Modern clinical practice requires the integration and interpretation of ever-expanding volumes of clinical data. There is, therefore, an imperative to develop efficient ways to process and understand these large amounts ... -
BMI and low vitamin D are causal factors for multiple sclerosis: A Mendelian Randomization study.
Jacobs, BM; Noyce, AJ; Giovannoni, G; Dobson, R (2020-03)OBJECTIVE: To update the causal estimates for the effects of adult body mass index (BMI), childhood BMI, and vitamin D status on multiple sclerosis (MS) risk. METHODS: We used 2-sample Mendelian randomization to determine ... -
Bone health in Parkinson's disease: a systematic review and meta-analysis
Torsney, KM; Noyce, AJ; Doherty, KM; Bestwick, JP; Dobson, R; Lees, AJ (2014-10) -
Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function
Noyce, AJ; Nagy, A; Acharya, S; Hadavi, S; Bestwick, JP; Fearnley, J; Lees, AJ; Giovannoni, G (2014-04-29) -
Brain health: The hidden casualty of a humanitarian crisis
Marshall, CR; Noyce, AJ; Neligan, A; Dobson, R (2022) -
Challenges of modifying disease progression in prediagnostic Parkinson's disease
Salat, D; Noyce, AJ; Schrag, A; Tolosa, E (2016-05) -
Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time
Neligan, A; Noyce, AJ; Gosavi, TD; Shorvon, SD; Köhler, S; Walker, MC (American Medical Association (AMA), 2019-08-01) -
Constipation preceding Parkinson's disease: a systematic review and meta-analysis
Adams-Carr, KL; Bestwick, JP; Shribman, S; Lees, A; Schrag, A; Noyce, AJ (2016-07) -
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
Mok, KY; Sheerin, U; Simón-Sánchez, J; Salaka, A; Chester, L; Escott-Price, V; Mantripragada, K; Doherty, KM; Noyce, AJ; Mencacci, NE (2016-05) -
Dementia risk in a diverse population: A single-region nested case-control study in the East End of London
Bothongo, PLK; Jitlal, M; Parry, E; Waters, S; Foote, IF; Watson, CJ; Cuzick, J; Giovannoni, G; Dobson, R; Noyce, AJ (2022) -
Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson's disease: a Distal Finger Tapping test
Akram, N; Li, H; Ben-Joseph, A; Budu, C; Gallagher, DA; Bestwick, JP; Schrag, A; Noyce, AJ; Simonet, C (2022) -
Development of Parkinson Disease and Its Relationship with Incidentally Discovered White Matter Disease and Covert Brain Infarction in a Real-World Cohort.
Kent, DM; Leung, LY; Puttock, EJ; Wang, AY; Luetmer, PH; Kallmes, DF; Nelson, J; Fu, S; Zheng, C; Vickery, EM (2022-10)OBJECTIVE: This study aimed to examine the relationship between covert cerebrovascular disease, comprised of covert brain infarction and white matter disease, discovered incidentally in routine care, and subsequent Parkinson ... -
Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study
Nalls, MA; McLean, CY; Rick, J; Eberly, S; Hutten, SJ; Gwinn, K; Sutherland, M; Martinez, M; Heutink, P; Williams, NM (Elsevier BV, 2015-10) -
Differences in the presentation and progression of Parkinson's disease by sex
Iwaki, H; Blauwendraat, C; Leonard, HL; Makarious, MB; Kim, JJ; Liu, G; Maple-Grødem, J; Corvol, J-C; Pihlstrøm, L; van Nimwegen, M (2020-04-11) -
Differences in the Presentation and Progression of Parkinson's Disease by Sex
Iwaki, H; Blauwendraat, C; Leonard, HL; Makarious, MB; Kim, JJ; Liu, G; Maple-Grodem, J; Corvol, J-C; Pihlstrom, L; van Nimwegen, M (Wiley, 2020-10-01) -
Dopamine reuptake transporter-single-photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease.
Noyce, AJ; Dickson, J; Rees, RN; Bestwick, JP; Isaias, IU; Politis, M; Giovannoni, G; Warner, TT; Lees, AJ; Schrag, A (2018-03)OBJECTIVE: The objective of this study was to examine whether prediagnostic features of Parkinson's disease (PD) were associated with changes in dopamine reuptake transporter-single-photon emission computed tomography and ...