Browsing Wolfson Institute of Preventive Medicine by Author "Foltynie, T"
Now showing items 1-8 of 8
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The Association Between Type 2 Diabetes Mellitus and Parkinson’s Disease
Cheong, J L Y; de Pablo-Fernandez, E; Foltynie, T; Noyce, A (IOS Press, 2020-04-24)In recent years, an emerging body of evidence has forged links between Parkinson’s disease (PD) and type 2 diabetes mellitus (T2DM). In observational studies, those with T2DM appear to be at increased risk of developing ... -
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
Mok, KY; Sheerin, U; Simón-Sánchez, J; Salaka, A; Chester, L; Escott-Price, V; Mantripragada, K; Doherty, KM; Noyce, AJ; Mencacci, NE (2016-05) -
Embedding Patient Input in Outcome Measures for Long-Term Disease-Modifying Parkinson Disease Trials.
Gonzalez-Robles, C; Bartlett, M; Burnell, M; Clarke, CS; Haar, S; Hu, MT; Huxford, B; Jha, A; Lawton, M; Noyce, A (2023-12-22)BACKGROUND: Clinical trials of disease-modifying therapies in PD require valid and responsive primary outcome measures that are relevant to patients. OBJECTIVES: The objective is to select a patient-centered primary outcome ... -
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study
Noyce, AJ; Kia, DA; Hemani, G; Nicolas, A; Price, TR; De Pablo-Fernandez, E; Haycock, PC; Lewis, PA; Foltynie, T; Davey Smith, G (Public Library of Science, 2017-06-13) -
Increased BMI May Protect against Parkinson's Disease: Evidence From Mendelian Randomisation Study
Noyce, A; Kia, D; Hemani, G; Nicolas, A; Price, T; Fernandez, E; Haycock, P; Lewis, P; Foltynie, T; Smith, GD (2017-06) -
Investigation of Autosomal Genetic Sex Differences in Parkinson's disease.
Blauwendraat, C; Iwaki, H; Makarious, MB; Bandres-Ciga, S; Leonard, H; Grenn, FP; Lake, J; Krohn, L; Tan, M; Kim, JJ (2021-04-26)OBJECTIVE: Parkinson's disease (PD) is a complex neurodegenerative disorder. Males are on average ~ 1.5 times more likely to develop PD compared to females with European ancestry. Over the years genome-wide association ... -
Outcome Measures for Disease-Modifying Trials in Parkinson's Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative
Gonzalez-Robles, C; Weil, RS; van Wamelen, D; Bartlett, M; Burnell, M; Clarke, CS; Hu, MT; Huxford, B; Jha, A; Lambert, C (2023) -
Technologies Assessing Limb Bradykinesia in Parkinson’s Disease
Hasan, H; Athauda, DS; Foltynie, T; Noyce, AJ (2017-02-07)Background: The MDS-UPDRS (Movement Disorders Society – Unified Parkinson’s Disease Rating Scale) is the most widely used scale for rating impairment in PD. Subscores measuring bradykinesia have low reliability that can ...