Awaiting Allocation: Recent submissions
Now showing items 21-40 of 247
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Object detection algorithms to identify skeletal components in carbonate cores
(2024-09-01)Identification of constituent grains in carbonate rocks requires specialist experience. A carbonate sedimentologist must be able to distinguish between skeletal grains that change through geological ages, preserved in ... -
Bioorthogonal Swarming: In Situ Generation of Dendrimers
(American Chemical Society, 2020-12-16)With the aid of bioorthogonal chemistry, we demonstrate the fabrication of synthetic dendrimers in situ around living cells. Using tetrazine dienophile and aminooxyl/hydrazide aldehyde chemistries, the density of functional ... -
Essential Emergency and Critical Care: a consensus among global clinical experts.
(BMJ Publishing Group, 2022-07-07)BACKGROUND: Globally, critical illness results in millions of deaths every year. Although many of these deaths are potentially preventable, the basic, life-saving care of critically ill patients are often overlooked in ... -
Development and validation of the highly sensitive child interview for the assessment of environmental sensitivity in primary school children
(Elsevier BV, 2024-02-22)Around a third of children perceive and process their environment more deeply and are more impacted by its quality. To obtain a more comprehensive and objective measure of this Environmental Sensitivity (ES) in primary ... -
Integrated care model for patients with functional somatic symptom disorder - a co-produced stakeholder exploration with recommendations for best practice.
(2024-06-03)BACKGROUND: Functional somatic symptoms (FFS) and bodily distress disorders are highly prevalent across all medical settings. Services for these patients are dispersed across the health care system with minimal conceptual ... -
Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease.
(2021)Objective and Impact Statement. There is a need to develop platforms delineating inflammatory biology of the distal human lung. We describe a platform technology approach to detect in situ enzyme activity and observe drug ... -
Self-healing multilayer films for simultaneous release of hydrophilic and hydrophobic drugs
(2021-01-01)Coloading and codelivery of hydrophilic and hydrophobic drugs as techniques for effective therapy have drawn attention but still present a challenge owing to the opposite nature of both drugs. Therefore, determining a ... -
Two-Photon Absorption: An Open Door to the NIR-II Biological Window?
(2022)The way in which photons travel through biological tissues and subsequently become scattered or absorbed is a key limitation for traditional optical medical imaging techniques using visible light. In contrast, near-infrared ... -
Hydrogel-based standards for single and multiphoton imaging at depth
(SPIE, the international society for optics and photonics, 2024-03-13) -
Molecular graph transformer: stepping beyond ALIGNN into long-range interactions
(Royal Society of Chemistry, 2024-04-23)Graph Neural Networks (GNNs) have revolutionized material property prediction by learning directly from the structural information of molecules and materials. However, conventional GNN models rely solely on local atomic ... -
A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data.
(Radcliffe Medical Media, 2024-05-20)Computational models of cardiac electrophysiology have gradually matured during the past few decades and are now being personalised to provide patient-specific therapy guidance for improving suboptimal treatment outcomes. ... -
Non-calcified plaque-based coronary stenosis grading in contrast enhanced CT
(Elsevier, 2024-05-22)Background: The high mortality rate associated with coronary heart disease has led to state-of-the-art non-invasive methods for cardiac diagnosis including computed tomography and magnetic resonance imaging. However, ... -
Capacitive PVC Gel Pressure Sensors with Various Interlinked Microstructural Dielectric Middle Layers
(Elsevier, 2024-05-22)Our sharp tactile sense is largely attributable to an undulating layer of microstructures between the epidermis and dermis, amplifying tactile signals. Taking inspiration from the biological template, we propose a design ... -
Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity.
(Hindawi, 2019-03-03)Citrate synthase (CS) is a key mitochondrial enzyme. The aim of this study was to test the hypothesis that low CS activity impairs the metabolic health of mice fed a high fat diet (HFD) and promotes palmitate-induced ... -
Pre-Exercise Rehydration Attenuates Central Fatigability during 2-Min Maximum Voluntary Contraction in Hyperthermia.
(MDPI, 2019-03-12)Background and objectives: Hyperthermia with dehydration alters several brain structure volumes, mainly by changing plasma osmolality, thus strongly affecting neural functions (cognitive and motor). Here, we aimed to examine ... -
Corrigendum to "Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity".
(Hindawi, 2019-08-01)[This corrects the article DOI: 10.1155/2019/8594825.]. -
Myostatin dysfunction does not protect from fasting-induced loss of muscle mass in mice.
(2019-09-01)OBJECTIVES: The aim of the study was to investigate if myostatin dysfunction can ameliorate fasting-induced muscle wasting. METHODS: 18-week old males from Berlin high (BEH) strain with myostatin dysfunction and wild type ... -
Caloric Restriction per se Rather Than Dietary Macronutrient Distribution Plays a Primary Role in Metabolic Health and Body Composition Improvements in Obese Mice.
(MDPI, 2021-08-28)Caloric restriction (CR) is of key importance in combating obesity and its associated diseases. We aimed to examine effects of dietary macronutrient distribution on weight loss and metabolic health in obese mice exposed ... -
Stanniocalcin-2 inhibits skeletal muscle growth and is upregulated in functional overload-induced hypertrophy.
(Wiley Open Access, 2023-08-11)AIMS: Stanniocalcin-2 (STC2) has recently been implicated in human muscle mass variability by genetic analysis. Biochemically, STC2 inhibits the proteolytic activity of the metalloproteinase PAPP-A, which promotes muscle ...