Browsing Chemistry and Biochemistry by Subject "Animals"
Now showing items 1-5 of 5
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Charting the host adaptation of influenza viruses.
(2011-06)Four influenza pandemics have struck the human population during the last 100 years causing substantial morbidity and mortality. The pandemics were caused by the introduction of a new virus into the human population from ... -
Estimating translational selection in eukaryotic genomes.
(2009-02)Natural selection on codon usage is a pervasive force that acts on a large variety of prokaryotic and eukaryotic genomes. Despite this, obtaining reliable estimates of selection on codon usage has proved complicated, perhaps ... -
The impact of the rate prior on Bayesian estimation of divergence times with multiple Loci.
(2014-07)Bayesian methods provide a powerful way to estimate species divergence times by combining information from molecular sequences with information from the fossil record. With the explosive increase of genomic data, divergence ... -
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II.
(2008-07-23)A class of putative Ras effectors called Ras association domain family (RASSF) represents non-enzymatic adaptors that were shown to be important in tumour suppression. RASSF5, a member of this family, exists in two splice ... -
Using non-homogeneous models of nucleotide substitution to identify host shift events: application to the origin of the 1918 'Spanish' influenza pandemic virus.
(2009-10)Nonhomogeneous Markov models of nucleotide substitution have received scant attention. Here we explore the possibility of using nonhomogeneous models to identify host shift nodes along phylogenetic trees of pathogens ...