Browsing Chemistry and Biochemistry by Issue Date
Now showing items 1-20 of 236
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Crystal structure of the Clostridium limosum C3 exoenzyme
(2008-04-02) -
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II.
(2008-07-23)A class of putative Ras effectors called Ras association domain family (RASSF) represents non-enzymatic adaptors that were shown to be important in tumour suppression. RASSF5, a member of this family, exists in two splice ... -
Estimating translational selection in eukaryotic genomes.
(2009-02)Natural selection on codon usage is a pervasive force that acts on a large variety of prokaryotic and eukaryotic genomes. Despite this, obtaining reliable estimates of selection on codon usage has proved complicated, perhaps ... -
Using non-homogeneous models of nucleotide substitution to identify host shift events: application to the origin of the 1918 'Spanish' influenza pandemic virus.
(2009-10)Nonhomogeneous Markov models of nucleotide substitution have received scant attention. Here we explore the possibility of using nonhomogeneous models to identify host shift nodes along phylogenetic trees of pathogens ... -
Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease.
(2011)The nigrostriatal dopaminergic (NSDA) pathway degenerates in Parkinson's disease (PD), which occurs with approximately twice the incidence in men than women. Studies of the influence of systemic estrogens in females suggest ... -
Charting the host adaptation of influenza viruses.
(2011-06)Four influenza pandemics have struck the human population during the last 100 years causing substantial morbidity and mortality. The pandemics were caused by the introduction of a new virus into the human population from ... -
Total Synthesis of Nominal Lyngbouilloside Aglycon
(2012-01-06)
