Browsing Chemistry and Biochemistry by Author "Jean, A"
Now showing items 1-3 of 3
-
Pd-Catalysed asymmetric allylic alkylation of heterocycles: a user's guide.
Richard, F; Clark, P; Hannam, A; Keenan, T; Jean, A; Arseniyadis, S (2024-01-11)This review provides an in-depth analysis of recent advances and strategies employed in the Pd-catalysed asymmetric allylic alkylation (Pd-AAA) of nucleophilic prochiral heterocycles. The review is divided into sections ... -
Synthesis of CHF2-Containing Heterocycles through Oxy-difluoromethylation Using Low-Cost 3D Printed PhotoFlow Reactors.
Zhang, J; Selmi-Higashi, E; Zhang, S; Jean, A; Hilton, ST; Cambeiro, XC; Arseniyadis, S (2024-01-08)We report here a highly straightforward access to a variety of CHF2-containing heterocycles, including lactones, tetrahydrofurans, tetrahydropyrans, benzolactones, phthalanes, and pyrrolidines, through a visible light-mediated ... -
Visible light-mediated difluoromethylation/cyclization in batch and flow: scalable synthesis of CHF2-containing benzimidazo- and indolo[2,1-a]isoquinolin-6(5H)-ones.
Hannam, A; Kankraisri, P; Thombare, KR; Meher, P; Jean, A; Hilton, ST; Murarka, S; Arseniyadis, S (Royal Society of Chemistry, 2024-07-03)We report here a practical and cost-effective method for the synthesis of CHF2-containing benzimidazo- and indolo[2,1,a]-isoquinolin-6(5H)-ones through a visible light-mediated difluoromethylation/cyclization cascade. The ...