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Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds
(Elsevier, 2016-07-19)
A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as anti-trypanosomatid agents. All tested compounds were ...
Finding direction in the search for selection
(Springer Verlag (Germany), 2016-11-29)
Novel 3-nitrotriazole-based amides and carbinols as bifunctional anti-Chagasic agents.
(American Chemical Society, 2015-01-23)
3-Nitro-1H-1,2,4-triazole-based amides with a linear, rigid core and 3-nitrotriazole-based fluconazole analogs were synthesized as dual functioning antitrypanosomal agents. Such compounds are excellent substrates for type ...
Can Dynamic Compression in the Absence of Growth Factors Induce Chondrogenic Differentiation of Bone Marrow Derived MSCs Encapsulated in Agarose Hydrogels?
(Springer Berlin Heidelberg, 2011)
The objectives of this study were twofold; to determine if cartilage specific matrix synthesis by mesenchymal stem cells (MSCs) is regulated by the magnitude and/or duration of dynamic compression in the absence of growth ...