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Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors

dc.contributor.authorDesiderio, MAen_US
dc.contributor.authorBergamaschi, Den_US
dc.contributor.authorMascellani, Een_US
dc.contributor.authorDeFeudis, Pen_US
dc.contributor.authorErba, Een_US
dc.contributor.authorDIncalci, Men_US
dc.date.accessioned2017-10-10T13:20:01Z
dc.date.issued1997-04en_US
dc.date.submitted2017-03-14T11:05:31.372Zreatment with inhibitors of polyamine bi
dc.identifier.issn0007-0920en_US
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/27343
dc.format.extent1028 - 1034en_US
dc.language.isoenen_US
dc.relation.ispartofBRITISH JOURNAL OF CANCERen_US
dc.rightsCreative Commons Attribution Non-Commercial Share Alike License
dc.subjectpolyaminesen_US
dc.subjectnovel inhibitor of ornithine decarboxylaseen_US
dc.subjectMAPen_US
dc.subjectinhibitor of SAMDCen_US
dc.subjectAbeAdoen_US
dc.subjectanti-cancer agentsen_US
dc.titleTreatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitorsen_US
dc.typeArticle
dc.rights.holder© 1997 Cancer Research Campaign.
dc.identifier.doi10.1038/bjc.1997.176en_US
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WQ68800013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue7en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume75en_US


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