Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors
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Volume
75
Pagination
1028 - 1034
DOI
10.1038/bjc.1997.176
Journal
BRITISH JOURNAL OF CANCER
Issue
ISSN
0007-0920