Search
Now showing items 31-40 of 342
Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems
(2007)
Embryonic development is regulated by a number of signalling pathways, Which are
critical for normal growth. Many of these genes then continue to play an important role
in the regulation of cell growth and differentiation ...
Understanding and Assessing the Therapeutic Relationship in Community Mental Health Care
(2006)
The clinician-patient relationship is at the core of community mental health care
and impacts on outcome, but no instrument has been specifically developed for
its assessmentE. xisting scalesh ave either unproven ...
Dual Tobacco Use in a Random Sample of UK Resident Bangladeshi Men
(2006)
UK resident Bangladeshi men pose a public health challenge because of their preference
for traditional tobacco use along side cigarette smoking. Studies investigating UK black
and minority ethnic tobacco use have not had ...
Studies of pathophysiology and psychosocial functioning in adolescents with anorectal anomalies
(2011)
Introduction: Anorectal anomalies (ARA) are a range of congenital conditions ranging
from a slight malposition of the anus to complex anomalies of the hindgut and urogenital
organ. Despite advanced surgical and treatment ...
Quality of life in intestinal failure
(2011)
Aims/objectives: The objectives of this research were to investigate and compare aspects
of Quality of Life (QoL) in adult patients who require HPN, in adult patients who have
pseudo-obstruction, and in carers of, and ...
Effect of anastrozole on bone mineral density and lipid profiles when used to prevent breast cancer in high risk postmenopausal women
(2012)
The role of aromatase inhibitors (AIs) in breast cancer has expanded since their introduction in
the mid-1990s. They are superior to tamoxifen in the treatment of postmenopausal women with
oestrogen dependant tumours in ...
Competing vulnerabilities in childhood cancer: the everyday lives of British Bangladeshi children with cancer.
(2008)
This thesis presents a social study of childhood cancer treatment in a group of British
Bangladeshi children living in one city in the United Kingdom.
It draws on theoretical perspectives that see childhood as a social ...
Psychological stress and hypnosis in ulcerative colitis.
(2008)
Previous studies suggest that life events and chronic stress increase the risk of
relapse in inflammatory bowel disease. Furthermore, experimental stress has been shown
to worsen inflammation in animal models of colitis. ...
Investigating the role of Bmi-1 in liver growth and function
(2011)
Bmi-1 is a member of the Polycomb group (PcG) family of transcriptional repressors, which are implicated in the maintenance of embryonic and adult stem cells. Previous reports indicate that Bmi-1 plays a key role in ...
Clinical and biological implications of ΔNp63α - an emerging therapeutic oncological target gene
(2011)
The p63 gene encodes multiple protein isoforms that function as sequence specific transcription factors, which can regulate both p53 dependent and independant target genes. Of these, ΔNp63α has been identified as one of ...