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    Quality of life in intestinal failure 
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    Quality of life in intestinal failure

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    CHAMBERSQualityOf2011.pdf (949.9Kb)
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    Abstract
    Aims/objectives: The objectives of this research were to investigate and compare aspects of Quality of Life (QoL) in adult patients who require HPN, in adult patients who have pseudo-obstruction, and in carers of, and children on, HPN. Methods: Demographic data, clinical parameters and current symptoms were collected and analysed. Generic QoL questionnaires were applied to the above groups. Results: HPN patients have significantly lower QoL than the rest of the UK population, report increased levels of bodily pain, anxiety and depression, a reduction in physical functioning, social functioning, general health, vitality and satisfactory levels of mental health and emotional functioning. Aspects of QoL improve over the first 6 months on HPN. Pseudo-obstruction has a negative impact on all aspects of QoL when compared to a normal population. A previous intestinal resection and opiate use had a negative impact on aspects of QoL. Carers of a child on HPN seek more social support and use more positive reappraisal coping strategies, more planful problem solving and less distancing than the controls and a higher level of psychiatric disorder is also seen. Children on HPN have a poorer functional status than those not on HPN, and there is a correlation between level of child dysfunction and parental general health. Families caring for a child on HPN function within normal and healthy parameters. Conclusions: Our studies indicate that the loss of intestinal function does have a negative impact on aspects of QoL but patients make adjustments to meet everyday requirements, even if it produces limitations with which these persons have to live by.
    Authors
    Chambers, Alison
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/2336
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