dc.contributor.author | Elneima, O | |
dc.contributor.author | Hurst, JR | |
dc.contributor.author | Echevarria, C | |
dc.contributor.author | Quint, JK | |
dc.contributor.author | Walker, S | |
dc.contributor.author | Siddiqui, S | |
dc.contributor.author | Novotny, P | |
dc.contributor.author | Pfeffer, PE | |
dc.contributor.author | Brown, JS | |
dc.contributor.author | Shankar-Hari, M | |
dc.contributor.author | McAuley, HJC | |
dc.contributor.author | Leavy, OC | |
dc.contributor.author | Shikotra, A | |
dc.contributor.author | Singapuri, A | |
dc.contributor.author | Sereno, M | |
dc.contributor.author | Richardson, M | |
dc.contributor.author | Saunders, RM | |
dc.contributor.author | Harris, VC | |
dc.contributor.author | Houchen-Wolloff, L | |
dc.contributor.author | Greening, NJ | |
dc.contributor.author | Harrison, EM | |
dc.contributor.author | Docherty, AB | |
dc.contributor.author | Lone, NI | |
dc.contributor.author | Chalmers, JD | |
dc.contributor.author | Ho, L-P | |
dc.contributor.author | Horsley, A | |
dc.contributor.author | Marks, M | |
dc.contributor.author | Poinasamy, K | |
dc.contributor.author | Raman, B | |
dc.contributor.author | Evans, RA | |
dc.contributor.author | Wain, LV | |
dc.contributor.author | Sheikh, A | |
dc.contributor.author | Brightling, CE | |
dc.contributor.author | De Soyza, A | |
dc.contributor.author | Heaney, LG | |
dc.date.accessioned | 2024-07-31T10:37:24Z | |
dc.date.available | 2024-03-06 | |
dc.date.available | 2024-07-31T10:37:24Z | |
dc.date.issued | 2024-07-15 | |
dc.identifier.citation | Elneima O, Hurst JR, Echevarria C, et al. Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study – PHOSP-COVID. ERJ Open Res 2024; 10: 00982-2023 [DOI: 10.1183/ 23120541.00982-2023]. | en_US |
dc.identifier.issn | 2312-0541 | |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/98486 | |
dc.description.abstract | BACKGROUND: The long-term outcomes of COVID-19 hospitalisation in individuals with pre-existing airway diseases are unknown. METHODS: Adult participants hospitalised for confirmed or clinically suspected COVID-19 and discharged between 5 March 2020 and 31 March 2021 were recruited to the Post-hospitalisation COVID-19 (PHOSP-COVID) study. Participants attended research visits at 5 months and 1 year post discharge. Clinical characteristics, perceived recovery, burden of symptoms and health-related quality of life (HRQoL) of individuals with pre-existing airway disease (i.e., asthma, COPD or bronchiectasis) were compared to the non-airways group. RESULTS: A total of 615 out of 2697 (22.8%) participants had a history of pre-existing airway diseases (72.0% diagnosed with asthma, 22.9% COPD and 5.1% bronchiectasis). At 1 year, the airways group participants were less likely to feel fully recovered (20.4% versus 33.2%, p<0.001), had higher burden of anxiety (29.1% versus 22.0%, p=0.002), depression (31.2% versus 24.7%, p=0.006), higher percentage of impaired mobility using short physical performance battery ≤10 (57.4% versus 45.2%, p<0.001) and 27% had a new disability (assessed by the Washington Group Short Set on Functioning) versus 16.6%, p=0.014. HRQoL assessed using EQ-5D-5L Utility Index was lower in the airways group (mean±SD 0.64±0.27 versus 0.73±0.25, p<0.001). Burden of breathlessness, fatigue and cough measured using a study-specific tool was higher in the airways group. CONCLUSION: Individuals with pre-existing airway diseases hospitalised due to COVID-19 were less likely to feel fully recovered, had lower physiological performance measurements, more burden of symptoms and reduced HRQoL up to 1 year post-hospital discharge. | en_US |
dc.language | eng | |
dc.publisher | European Respiratory Society (ERS) | en_US |
dc.relation | ©The authors 2024 | |
dc.relation.ispartof | ERJ Open Res | |
dc.rights | This version is distributed under the terms of the Creative Commons Attribution Licence 4.0 | |
dc.title | Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study - PHOSP-COVID. | en_US |
dc.type | Article | en_US |
dc.rights.holder | ©The authors 2024 | |
dc.identifier.doi | 10.1183/23120541.00982-2023 | |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/39010888 | en_US |
pubs.issue | 4 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published online | en_US |
pubs.volume | 10 | en_US |
dcterms.dateAccepted | 2024-03-06 | |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |
qmul.funder | PHOSP-COVID Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes::UK Research and Innovation | en_US |
rioxxterms.funder.project | b215eee3-195d-4c4f-a85d-169a4331c138 | en_US |