dc.contributor.author | Shaw, PA | en_US |
dc.contributor.author | Forsyth, E | en_US |
dc.contributor.author | Haseeb, F | en_US |
dc.contributor.author | Yang, S | en_US |
dc.contributor.author | Bradley, M | en_US |
dc.contributor.author | Klausen, M | en_US |
dc.date.accessioned | 2024-06-04T08:52:56Z | |
dc.date.available | 2022-05-04 | en_US |
dc.date.issued | 2022 | en_US |
dc.identifier.issn | 2296-2646 | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/97222 | |
dc.description.abstract | The way in which photons travel through biological tissues and subsequently become scattered or absorbed is a key limitation for traditional optical medical imaging techniques using visible light. In contrast, near-infrared wavelengths, in particular those above 1000 nm, penetrate deeper in tissues and undergo less scattering and cause less photo-damage, which describes the so-called "second biological transparency window". Unfortunately, current dyes and imaging probes have severely limited absorption profiles at such long wavelengths, and molecular engineering of novel NIR-II dyes can be a tedious and unpredictable process, which limits access to this optical window and impedes further developments. Two-photon (2P) absorption not only provides convenient access to this window by doubling the absorption wavelength of dyes, but also increases the possible resolution. This review aims to provide an update on the available 2P instrumentation and 2P luminescent materials available for optical imaging in the NIR-II window. | en_US |
dc.format.extent | 921354 - ? | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Front Chem | en_US |
dc.rights | This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | |
dc.subject | fluorescent imaging | en_US |
dc.subject | infrared dyes | en_US |
dc.subject | near-infrared II | en_US |
dc.subject | pulsed lasers | en_US |
dc.subject | tissue penetration | en_US |
dc.subject | two-photon absorption | en_US |
dc.subject | two-photon microscopy | en_US |
dc.title | Two-Photon Absorption: An Open Door to the NIR-II Biological Window? | en_US |
dc.type | Article | |
dc.rights.holder | © 2022 Shaw, Forsyth, Haseeb, Yang, Bradley and Klausen | |
dc.identifier.doi | 10.3389/fchem.2022.921354 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/35815206 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published online | en_US |
pubs.volume | 10 | en_US |
dcterms.dateAccepted | 2022-05-04 | en_US |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |
qmul.funder | Lighting the Way to a Healthy Nation - Optical 'X-rays' for Walk Through Diagnosis & Therapy::Engineering and Physical Sciences Research Council | en_US |
qmul.funder | Lighting the Way to a Healthy Nation - Optical 'X-rays' for Walk Through Diagnosis & Therapy::Engineering and Physical Sciences Research Council | en_US |
qmul.funder | Lighting the Way to a Healthy Nation - Optical 'X-rays' for Walk Through Diagnosis & Therapy::Engineering and Physical Sciences Research Council | en_US |
qmul.funder | Lighting the Way to a Healthy Nation - Optical 'X-rays' for Walk Through Diagnosis & Therapy::Engineering and Physical Sciences Research Council | en_US |