| dc.contributor.author | McCarthy, RL | |
| dc.contributor.author | de Brito, M | |
| dc.contributor.author | O'Toole, EA | |
| dc.date.accessioned | 2024-05-31T12:17:44Z | |
| dc.date.available | 2024-05-27 | |
| dc.date.available | 2024-05-31T12:17:44Z | |
| dc.date.issued | 2024-05-28 | |
| dc.identifier.citation | Rebecca L McCarthy, Marianne de Brito, Edel A O’Toole, Pachyonychia congenita – pathogenesis of pain and approaches to treatment, Clinical and Experimental Dermatology, 2024;, llae199, https://doi.org/10.1093/ced/llae199 | en_US |
| dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/97144 | |
| dc.description.abstract | Pachyonychia congenita is an autosomal dominant genodermatosis characterized by a triad of chronic severe plantar pain, focal palmoplantar keratoderma, and hypertrophic nail dystrophy. Plantar pain can be debilitating and have a profound impact on quality of life. Current therapeutic options for pain in PC are limited to lifestyle adjustment and mechanical techniques, with a small subgroup of patients benefiting from oral retinoids. This review investigates the pathogenesis of pain in pachyonychia congenita and provides a summary of the current and future therapeutic options. | en_US |
| dc.language | eng | |
| dc.publisher | Oxford University Press | en_US |
| dc.relation.ispartof | Clin Exp Dermatol | |
| dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. | |
| dc.title | Pachyonychia congenita - pathogenesis of pain and approaches to treatment. | en_US |
| dc.type | Article | en_US |
| dc.rights.holder | © The Author(s) 2024. Published by Oxford University Press on behalf of British Association of Dermatologists. | |
| dc.identifier.doi | 10.1093/ced/llae199 | |
| pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/38805703 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published online | en_US |
| dcterms.dateAccepted | 2024-05-27 | |
| rioxxterms.funder | Default funder | en_US |
| rioxxterms.identifier.project | Default project | en_US |
