dc.contributor.author | Onwuka, SR | en_US |
dc.contributor.author | Boyd, L | en_US |
dc.contributor.author | Wijesuriya, R | en_US |
dc.contributor.author | Broun, K | en_US |
dc.contributor.author | Marker, J | en_US |
dc.contributor.author | Shub, M | en_US |
dc.contributor.author | McIntosh, JG | en_US |
dc.contributor.author | Macrae, F | en_US |
dc.contributor.author | Chondros, P | en_US |
dc.contributor.author | Saya, S | en_US |
dc.contributor.author | Novy, K | en_US |
dc.contributor.author | Jenkins, MA | en_US |
dc.contributor.author | Walter, FM | en_US |
dc.contributor.author | Trevena, L | en_US |
dc.contributor.author | Martinez Gutierrez, J | en_US |
dc.contributor.author | Fishman, G | en_US |
dc.contributor.author | Emery, J | en_US |
dc.date.accessioned | 2024-03-27T09:09:57Z | |
dc.date.available | 2024-03-14 | en_US |
dc.date.issued | 2024-03-25 | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/95782 | |
dc.description.abstract | Background Australian guidelines recommend that all people aged 50-70 years old consider taking low-dose aspirin to reduce the risk of colorectal cancer (CRC). Aim To determine the effect of a consultation with a researcher in general practice using a decision aid about taking low-dose aspirin to prevent CRC on informed decision-making and low-dose aspirin uptake compared to a general CRC prevention brochure. Design and Setting Individually randomised controlled trial in six general practices in Victoria, Australia, from October 2020 to March 2021. Method Patients aged 50-70 years attending a general practitioner (GP) were recruited consecutively. The intervention was a consultation using a decision aid to discuss taking aspirin to reduce CRC risk; control consultations discussed reducing CRC risk generally. The self-reported co-primary outcomes were informed choices about taking aspirin at one month and low-dose aspirin uptake at six months. Results 261 participants (86% of eligible patients) were randomised into trial arms (129 intervention, 132 control). 17.7% (20/113) of intervention and 7.6% (9/118) control participants reported making an informed choice at one month, an estimated 9.1% (95% CI 0.29% to 18.5) between-arm difference in proportions [odds ratio (OR) 2.47 (97.5% CI:0.94 to 6.52) p=0.074]. The proportions of individuals who reported using aspirin at six months were: 10.2% (12/118) intervention vs 13.8% (16/116) control (estimated between-arm difference: -4.0% (95% CI: -13.5 to 5.5); [OR= 0.68 (97.5% CI:0.27 to 1.70), p= 0.692]. Conclusion The decision aid improved informed decision-making; but has little effect on long-term regular use of aspirin to reduce CRC risk. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Br J Gen Pract | en_US |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/). Published by British Journal of General Practice. | |
dc.title | Should I Take Aspirin? (SITA): RCT of a decision aid for cancer chemoprevention. | en_US |
dc.type | Article | |
dc.rights.holder | © 2024 The Author(s). | |
dc.identifier.doi | 10.3399/BJGP.2023.0385 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/38527793 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published online | en_US |
dcterms.dateAccepted | 2024-03-14 | en_US |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |