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dc.contributor.authorHe, Y
dc.contributor.authorZamani, E
dc.contributor.authorYevseyeva, I
dc.contributor.authorLuo, C
dc.date.accessioned2023-12-19T12:03:14Z
dc.date.available2023-01-19
dc.date.available2023-12-19T12:03:14Z
dc.date.issued2023-04-25
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/93054
dc.description.abstractBACKGROUND: Health information systems (HISs) are continuously targeted by hackers, who aim to bring down critical health infrastructure. This study was motivated by recent attacks on health care organizations that have resulted in the compromise of sensitive data held in HISs. Existing research on cybersecurity in the health care domain places an imbalanced focus on protecting medical devices and data. There is a lack of a systematic way to investigate how attackers may breach an HIS and access health care records. OBJECTIVE: This study aimed to provide new insights into HIS cybersecurity protection. We propose a systematic, novel, and optimized (artificial intelligence-based) ethical hacking method tailored specifically for HISs, and we compared it with the traditional unoptimized ethical hacking method. This allows researchers and practitioners to identify the points and attack pathways of possible penetration attacks on the HIS more efficiently. METHODS: In this study, we propose a novel methodological approach to ethical hacking in HISs. We implemented ethical hacking using both optimized and unoptimized methods in an experimental setting. Specifically, we set up an HIS simulation environment by implementing the open-source electronic medical record (OpenEMR) system and followed the National Institute of Standards and Technology's ethical hacking framework to launch the attacks. In the experiment, we launched 50 rounds of attacks using both unoptimized and optimized ethical hacking methods. RESULTS: Ethical hacking was successfully conducted using both optimized and unoptimized methods. The results show that the optimized ethical hacking method outperforms the unoptimized method in terms of average time used, the average success rate of exploit, the number of exploits launched, and the number of successful exploits. We were able to identify the successful attack paths and exploits that are related to remote code execution, cross-site request forgery, improper authentication, vulnerability in the Oracle Business Intelligence Publisher, an elevation of privilege vulnerability (in MediaTek), and remote access backdoor (in the web graphical user interface for the Linux Virtual Server). CONCLUSIONS: This research demonstrates systematic ethical hacking against an HIS using optimized and unoptimized methods, together with a set of penetration testing tools to identify exploits and combining them to perform ethical hacking. The findings contribute to the HIS literature, ethical hacking methodology, and mainstream artificial intelligence-based ethical hacking methods because they address some key weaknesses of these research fields. These findings also have great significance for the health care sector, as OpenEMR is widely adopted by health care organizations. Our findings offer novel insights for the protection of HISs and allow researchers to conduct further research in the HIS cybersecurity domain.en_US
dc.format.extente41748 - ?
dc.languageeng
dc.publisherJMIRen_US
dc.relation.ispartofJ Med Internet Res
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectAI-based hackingen_US
dc.subjectHISen_US
dc.subjectOpenEMRen_US
dc.subjectartificial intelligenceen_US
dc.subjectcyber defense solutionsen_US
dc.subjectethical hackingen_US
dc.subjecthealth information systemen_US
dc.subjectopen-source electronic medical recorden_US
dc.subjectHumansen_US
dc.subjectArtificial Intelligenceen_US
dc.subjectHealth Information Systemsen_US
dc.subjectElectronic Health Recordsen_US
dc.subjectComputer Securityen_US
dc.subjectSoftwareen_US
dc.titleArtificial Intelligence-Based Ethical Hacking for Health Information Systems: Simulation Study.en_US
dc.typeArticleen_US
dc.rights.holder©Ying He, Efpraxia Zamani, Iryna Yevseyeva, Cunjin Luo. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 25.04.2023.
dc.identifier.doi10.2196/41748
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37097723en_US
pubs.notesNot knownen_US
pubs.publication-statusPublished onlineen_US
pubs.volume25en_US
dcterms.dateAccepted2023-01-19
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.
Except where otherwise noted, this item's license is described as This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.