Peptide probes for proteases - innovations and applications for monitoring proteolytic activity.

dc.contributor.author	Rodriguez-Rios, M
dc.contributor.author	Megia-Fernandez, A
dc.contributor.author	Norman, DJ
dc.contributor.author	Bradley, M
dc.date.accessioned	2023-09-27T11:02:37Z
dc.date.available	2023-09-27T11:02:37Z
dc.date.issued	2022-03-21
dc.identifier.uri	https://qmro.qmul.ac.uk/xmlui/handle/123456789/90951
dc.description.abstract	Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for diagnostic applications and are valuable targets for therapy. From a chemistry-based perspective this review discusses and critiques the most recent advances in the field of substrate-based probes for the detection and analysis of proteolytic activity both in vitro and in vivo.	en_US
dc.format.extent	2081 - 2120
dc.language	eng
dc.relation.ispartof	Chem Soc Rev
dc.rights	Attribution 3.0 United States	*
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/us/	*
dc.subject	Biomarkers	en_US
dc.subject	Peptide Hydrolases	en_US
dc.subject	Peptides	en_US
dc.subject	Proteolysis	en_US
dc.title	Peptide probes for proteases - innovations and applications for monitoring proteolytic activity.	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1039/d1cs00798j
pubs.author-url	https://www.ncbi.nlm.nih.gov/pubmed/35188510	en_US
pubs.issue	6	en_US
pubs.notes	Not known	en_US
pubs.publication-status	Published online	en_US
pubs.volume	51	en_US

Except where otherwise noted, this item's license is described as Attribution 3.0 United States