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dc.contributor.authorAlonso, S
dc.contributor.authorTan, M
dc.contributor.authorWang, C
dc.contributor.authorKent, S
dc.contributor.authorCobiac, L
dc.contributor.authorMacGregor, GA
dc.contributor.authorHe, FJ
dc.contributor.authorMihaylova, B
dc.date.accessioned2021-06-01T16:58:05Z
dc.date.available2021-01-18
dc.date.available2021-06-01T16:58:05Z
dc.date.issued2021-03-01
dc.identifier.issn0194-911X
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/72199
dc.description.abstractThe United Kingdom was among the first countries to introduce a salt reduction program in 2003 to reduce cardiovascular disease (CVD) incidence risk. Despite its initial success, the program has stalled recently and is yet to achieve national and international targets. We used age- and sex-stratified salt intake of 19 to 64 years old participants in the National Diet and Nutrition Surveys 2000 to 2018 and a multistate life table model to assess the effects of the voluntary dietary salt reduction program on premature CVD, quality-adjusted survival, and health care and social care costs in England. The program reduced population-level salt intake from 9.38 grams/day per adult (SE, 0.16) in 2000 to 8.38 grams/day per adult (SE, 0.17) in 2018. Compared with a scenario of persistent 2000 levels, assuming that the population-level salt intake is maintained at 2018 values, by 2050, the program is projected to avoid 83 140 (95% CI, 73 710–84 520) premature ischemic heart disease (IHD) cases and 110 730 (95% CI, 98 390–112 260) premature strokes, generating 542 850 (95% CI, 529 020–556 850) extra quality-adjusted life-years and £1640 million (95% CI, £1570–£1660) health care cost savings for the adult population of England. We also projected the gains of achieving the World Health Organization target of 5 grams/day per adult by 2030, which by 2050 would avert further 87 870 (95% CI, 82 050–88 470) premature IHD cases, 126 010 (95% CI, 118 600–126 460) premature strokes and achieve £1260 million (95% CI, £1180–£1260) extra health care savings compared with maintaining 2018 levels. Strengthening the salt reduction program to achieve further reductions in population salt intake and CVD burden should be a high priority.en_US
dc.format.extent1086 - 1094
dc.publisherWolters Kluwer Health, Inc.en_US
dc.relation.ispartofHYPERTENSION
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.
dc.subjectcardiovascular diseaseen_US
dc.subjectdieten_US
dc.subjecthealth care costen_US
dc.subjectincidenceen_US
dc.subjectischemic heart diseaseen_US
dc.subjectsalt reductionen_US
dc.subjectstrokeen_US
dc.subjectUnited Kingdomen_US
dc.titleImpact of the 2003 to 2018 Population Salt Intake Reduction Program in England A Modeling Studyen_US
dc.typeArticleen_US
dc.rights.holder© 2021 The Authors. Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc.
dc.identifier.doi10.1161/HYPERTENSIONAHA.120.16649
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000639315900013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue4en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.publisher-urlhttps://doi.org/10.1161/HYPERTENSIONAHA.120.16649
pubs.volume77en_US
dcterms.dateAccepted2021-01-18
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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