| dc.contributor.author | Saengkaew, T | en_US |
| dc.contributor.author | Howard, SR | en_US |
| dc.date.accessioned | 2020-08-24T11:11:38Z | |
| dc.date.issued | 2020-10-01 | en_US |
| dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/66556 | |
| dc.description.abstract | © 2020 Elsevier Ltd The inheritance of pubertal timing is strongly influenced by genetic regulators, with conditions of delayed or absent puberty segregating within families often with Mendelian inheritance patterns. As such, these conditions are amenable to genetic discovery through next-generation sequencing. This review covers the significant advances in understanding of the biological mechanisms of delayed puberty that have occurred in the last 5–10 years with the use of this technology. | en_US |
| dc.format.extent | 59 - 64 | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Current Opinion in Endocrine and Metabolic Research | en_US |
| dc.rights | © 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.title | Next-generation sequencing approach in the diagnosis of delayed puberty | en_US |
| dc.type | Article | |
| dc.identifier.doi | 10.1016/j.coemr.2020.05.003 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published | en_US |
| pubs.volume | 14 | en_US |
| rioxxterms.funder | Default funder | en_US |
| rioxxterms.identifier.project | Default project | en_US |
| qmul.funder | Investigation of the genetic basis of disordered pubertal timing::Rosetrees Trust | en_US |
