Browsing Centre for Clinical Trials & Methodology by Title
Now showing items 241-260 of 263
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Tailored psychological intervention for anxiety or depression in COPD (TANDEM): a randomised controlled trial.
(2023-08-24)This multi-centre, pragmatic, randomised controlled trial evaluated whether a tailored psychological intervention based on a cognitive behavioural approach for people with COPD and symptoms of anxiety and/or depression ... -
Termination of pregnancy data completeness and feasibility in population-based surveys: EN-INDEPTH study
(BioMed Central, 2021-02)Background Termination of pregnancy (TOP) is a common cause of maternal morbidity and mortality in low- and middle-income countries. Population-based surveys are the major data source for TOP data in LMICs but are known ... -
Topical anti-inflammatory treatments for eczema: network meta-analysis
(2022-07-28)Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To compare the efficacy and safety of topical anti-inflammatory treatments for reducing eczema symptoms or signs or ... -
Trait Anxiety and Economic Risk Avoidance Are Not Necessarily Associated: Evidence from the Framing Effect.
(2017)According to previous literature, trait anxiety is related to the tendency to choose safety options during risk decision-making, that is, risk avoidance. In our opinion, anxious people's risk preference might actually ... -
Transparency of informed consent in pilot and feasibility studies is inadequate: a single-center quality assurance study.
(BioMed Central, 2021-04-16)BACKGROUND: Pilot and feasibility studies (PAFS) often have complex objectives aimed at assessing feasibility of conducting a larger study. These may not be clear to participants in pilot studies. METHODS: Here, we aimed ... -
A tutorial on sample size calculation for multiple-period cluster randomized parallel, cross-over and stepped-wedge trials using the Shiny CRT Calculator.
(2020-06-01)It has long been recognized that sample size calculations for cluster randomized trials require consideration of the correlation between multiple observations within the same cluster. When measurements are taken at anything ... -
Understanding GPs' views and experiences of using clinical prediction rules in the management of respiratory infections: a qualitative study.
(2021-08)BACKGROUND: Respiratory tract infections (RTIs) account for 60% of antibiotic prescribing in primary care. Several clinical prediction rules (CPRs) have been developed to help reduce unnecessary prescribing for RTIs, but ... -
Using microbiological data to improve the use of antibiotics for respiratory tract infections: A protocol for an individual patient data meta-analysis.
(2023)BACKGROUND: Resistance to antibiotics is rising and threatens future antibiotic effectiveness. 'Antibiotic targeting' ensures patients who may benefit from antibiotics receive them, while being safely withheld from those ... -
Using the right words to address racial disparities in COVID-19
(Elsevier BV, 2020-08) -
Uterotonics for prevention of postpartum haemorrhage: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Postpartum haemorrhage (PPH) is a leading cause of preventable maternal mortality worldwide. The World Health Organization (WHO) recommends uterotonic administration for every woman after birth to prevent PPH. ...