Browsing Centre for Clinical Trials & Methodology by Title
Now showing items 95-114 of 263
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Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial.
(American Medical Association, 2020-05-07)Importance: The value of facedown positioning following surgery for large full-thickness macular holes is unknown. Objective: To determine whether advice to position facedown postoperatively improves the outcome for large ... -
A feasibility trial of a digital mindfulness-based intervention to improve asthma-related quality of life for primary care patients with asthma.
(2022-02)Asthma outcomes remain suboptimal, despite effective pharmacotherapy. Psychological dysfunction (such as anxiety) is common, and associated with poorer outcomes. We evaluated a digital mindfulness programme as an intervention ... -
FORWARDS-1: an adaptive, single-blind, placebo-controlled ascending dose study of acute baclofen on safety parameters in opioid dependence during methadone-maintenance treatment-a pharmacokinetic-pharmacodynamic study.
(2022-10-18)BACKGROUND: Treatment of opiate addiction with opiate substitution treatment (e.g. methadone) is beneficial. However, some individuals desire or would benefit from abstinence but there are limited options to attenuate ... -
Four decades of measuring stillbirths and neonatal deaths in Demographic and Health Surveys: historical review
(Springer Science and Business Media LLC, 2021-02-08)Background Worldwide, an estimated 5.1 million stillbirths and neonatal deaths occur annually, 98% in low- and middle-income countries. Limited coverage of civil and vital registration systems necessitates reliance on ... -
Fresh street: the development and feasibility of a place-based, subsidy for fresh fruit and vegetables.
(Oxford University Press (OUP), 2020-11-09)BACKGROUND: Many UK communities experience food insecurity, and consume diets high in energy-dense, nutrient poor, processed foods and low in fruit and vegetables (FV). We explored a novel area-based approach to promote ... -
Gestational age data completeness, quality and validity in population-based surveys: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Preterm birth (gestational age (GA) <37 weeks) is the leading cause of child mortality worldwide. However, GA is rarely assessed in population-based surveys, the major data source in low/middle-income countries. ... -
Health insurance enrollment strategies during the Affordable Care Act (ACA): a scoping review on what worked and for whom.
(BMC part of Springer Nature, 2021-07-12)BACKGROUND: The Affordable Care Act (ACA) provided an opportunity for millions of people in the U.S. to get coverage from the publicly funded Medicaid program or private insurance from the newly established marketplace. ... -
Health System Trials
(2019) -
Hypofractionation: The standard for external beam breast irradiation.
(2023-06)This overview provides the historical perspective of external beam breast hypofractionation over the last 50 years. It highlights the serious harm suffered by patients with breast cancer in the 1970's and 1980's because ...