Browsing Centre for Clinical Trials & Methodology by Title
Now showing items 146-165 of 263
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MO589: Exertion2 Trial: THE Weight Gain Prevention in Renal Transplant Online Study—a Randomized Controlled Feasibility Trial
(Oxford University Press (OUP), 2022-05-03) -
A model of lifetime health outcomes in cardiovascular disease based on clinical trials and large cohorts
(Oxford University Press (OUP), 2021-10-12)<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background and purpose</jats:title> <jats:p>Cardiovascular disease (CVD) risk of individuals depends on their socio-demographic characteristics, clinical risk factors, ... -
Moving towards malaria elimination in southern Mozambique: Cost and cost-effectiveness of mass drug administration combined with intensified malaria control.
(2020)BACKGROUND: As new combinations of interventions aiming at interrupting malaria transmission are under evaluation, understanding the associated economic costs and benefits is critical for decision-making. This study assessed ... -
Neonatal and child mortality data in retrospective population-based surveys compared with prospective demographic surveillance: EN-INDEPTH study.
(BMC part of Springer Nature, 2021-02-08)BACKGROUND: Global mortality estimates remain heavily dependent on household surveys in low- and middle-income countries, where most under-five deaths occur. Few studies have assessed the accuracy of mortality data or ... -
Neonatal resuscitation: EN-BIRTH multi-country validation study.
(BioMed Central, 2021-03-26)BACKGROUND: Annually, 14 million newborns require stimulation to initiate breathing at birth and 6 million require bag-mask-ventilation (BMV). Many countries have invested in facility-based neonatal resuscitation equipment ... -
Nonlinear effects and effect modification at the participant-level in IPD meta-analysis part 1: analysis methods are often substandard.
(2023-05-04)OBJECTIVES: To review analysis methods used for linear effect modification (LEM), nonlinear covariate-outcome associations (NL) and nonlinear effect modification (NLEM) at the participant-level in individual participant ... -
One versus three weeks hypofractionated whole breast radiotherapy for early breast cancer treatment: the FAST-Forward phase III RCT.
(2023-11)BACKGROUND: FAST-Forward aimed to identify a 5-fraction schedule of adjuvant radiotherapy delivered in 1 week that was non-inferior in terms of local cancer control and as safe as the standard 15-fraction regimen after ... -
One versus three weeks hypofractionated whole breast radiotherapy for early breast cancer treatment: the FAST-Forward phase III RCT.
(NIHR Journals Library, 2023-11-21) -
An optimization framework to guide the choice of thresholds for risk-based cancer screening.
(2023-11-28)It is uncommon for risk groups defined by statistical or artificial intelligence (AI) models to be chosen by jointly considering model performance and potential interventions available. We develop a framework to rapidly ... -
Paradata analyses to inform population-based survey capture of pregnancy outcomes: EN-INDEPTH study
(BioMed Central, 2021-02-08)Background: Paradata are (timestamped) records tracking the process of (electronic) data collection. We analysed paradata from a large household survey of questions capturing pregnancy outcomes to assess performance ...