Browsing Centre for Clinical Trials & Methodology by Title
Now showing items 118-137 of 263
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Impact of implementing the aseptic compounding management system, Medcura, on internal error rates within an oncology pharmacy aseptic unit: a mixed methods evaluation.
(2022-10-14)BACKGROUND: As cancer survivorship improves, pressure on oncology services to provide safe, timely treatments increases. Traditional manual compounding processes are error prone, putting patients at risk. Additionally, ... -
Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform.
(2023-12-04)BACKGROUND: Germ Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively ... -
The importance of different frailty domains in a population based sample in England
(BioMed Central, 2020-01-15)Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ... -
Incidence rate and financial burden of medical errors and policy interventions to address them: a multi-method study protocol
(Springer Science and Business Media LLC, 2021-11-05)Medical error is one of the most critical challenges facing medical services. They pose a substantial threat to patient safety, and their costs draw attention from policymakers, health care planners and researchers. We aim ... -
Informal payments for inpatient health care in post-health transformation plan period: evidence from Iran
(Springer Science and Business Media LLC, 2020-04-20)Background: In 2014, a revision of the national medical tariffs for inpatient health care services took place in Iran, and a new hotline was set up to report informal payments. It was expected that such measures would ... -
Innate and adaptive mucosal immunity in protection against HIV infection.
(2006-04-01)The appalling toll on the populations of developing countries as a result of the HIV epidemic shows no signs of abatement. While costly drug therapies are effective in developed nations, the sheer scale of the epidemic ... -
Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial.
(2023-11-09)OBJECTIVE: To investigate whether intravenous immunoglobulin (IVIG) improves neurological outcomes in children with encephalitis when administered early in the illness. DESIGN: Phase 3b multicentre, double-blind, randomised ... -
IP-10 Levels as an Accurate Screening Tool to Detect Acute HIV Infection in Resource-Limited Settings.
(2017-08-14)Acute HIV infection (AHI) is the period prior to seroconversion characterized by high viral replication, hyper-transmission potential and commonly, non-specific febrile illness. AHI detection requires HIV-RNA viral load ... -
Iran health insurance system in transition: equity concerns and steps to achieve universal health coverage.
(2021-01-14)<h4>Background</h4>Equity, efficiency, sustainability, acceptability to clients and providers, and quality are the cornerstones of universal health coverage (UHC). No country has a single way to achieve efficient UHC. In ... -
Kangaroo mother care: EN-BIRTH multi-country validation study.
(2021-03-26)BACKGROUND: Kangaroo mother care (KMC) reduces mortality among stable neonates ≤2000 g. Lack of data tracking coverage and quality of KMC in both surveys and routine information systems impedes scale-up. This paper evaluates ... -
Key concepts in clinical epidemiology: Stepped wedge trials
(Elsevier, 2021-04-20)