dc.contributor.author | Darlow, BA | en_US |
dc.contributor.author | Husain, S | en_US |
dc.date.accessioned | 2019-08-20T09:28:50Z | |
dc.date.issued | 2019-10 | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/59228 | |
dc.description.abstract | Reducing the burden of visual morbidity from retinopathy of prematurity (ROP) begins with primary prevention, and improvements in neonatal care with a positive impact on ROP are possible in all settings. Strategies range from rigorous adoption of inexpensive evidence-based protocols, for example on temperature control, prevention of sepsis and support for breast-milk feeding, through to comprehensive quality improvement programmes, and fostering team work and camaraderie. Oxygen monitoring is essential for very preterm infants receiving supplementary oxygen. The Neonatal Oxygenation Prospective Meta-analysis (NeOProM) collaboration has reported analysis of five trials of oxygen saturation (SpO2) targeting in very preterm infants and shown that a SpO2 target of 85-89% compared to 91-95% was associated with increased mortality (on average 28 extra deaths for every 1000 infants treated). Adopting a SpO2 target higher than 85-89% might increase the risk of ROP for some infants, highlighting the importance of pursuing all other means of prevention. | en_US |
dc.format.extent | 333 - 340 | en_US |
dc.language | eng | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Semin Perinatol | en_US |
dc.subject | Middle-income countries | en_US |
dc.subject | Oxygen saturation targeting | en_US |
dc.subject | Prevention of morbidity | en_US |
dc.subject | Randomised controlled trials | en_US |
dc.subject | Retinopathy of prematurity | en_US |
dc.subject | Very preterm infants | en_US |
dc.title | Primary prevention of ROP and the oxygen saturation targeting trials. | en_US |
dc.type | Article | |
dc.identifier.doi | 10.1053/j.semperi.2019.05.004 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/31151776 | en_US |
pubs.issue | 6 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 43 | en_US |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |