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dc.contributor.authorGhimire, Ben_US
dc.contributor.authorMaroni, Ren_US
dc.contributor.authorVulkan, Den_US
dc.contributor.authorShah, Zen_US
dc.contributor.authorGaynor, Een_US
dc.contributor.authorTimoney, Men_US
dc.contributor.authorJones, Len_US
dc.contributor.authorArvanitis, Ren_US
dc.contributor.authorLedson, Men_US
dc.contributor.authorLukehirst, Len_US
dc.contributor.authorRutherford, Pen_US
dc.contributor.authorClarke, Fen_US
dc.contributor.authorGardner, Ken_US
dc.contributor.authorMarcus, MWen_US
dc.contributor.authorHill, Sen_US
dc.contributor.authorFidoe, Den_US
dc.contributor.authorMason, Sen_US
dc.contributor.authorSmith, SGen_US
dc.contributor.authorQuaife, SLen_US
dc.contributor.authorFitzgerald, Ken_US
dc.contributor.authorPoirier, Ven_US
dc.contributor.authorDuffy, SWen_US
dc.contributor.authorField, JKen_US
dc.date.accessioned2019-08-09T16:28:08Z
dc.date.available2019-05-26en_US
dc.date.issued2019-08en_US
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/58971
dc.description.abstractOBJECTIVES: This Liverpool Healthy Lung Programme is a response to high rates of lung cancer and respiratory diseases locally and aims to diagnose lung cancer at an earlier stage by proactive approach to those at high risk of lung cancer. The objective of this study is to evaluate the programme in terms of its likely effect on mortality from lung cancer and its delivery to deprived populations. METHODS: Persons aged 58-75 years, with a history of smoking or a diagnosis of chronic obstructive pulmonary disease (COPD)2 according to general practice records were invited for lung health check in a community health hub setting. A detailed risk assessment and spirometry were performed in eligible patients. Those with a 5% or greater five-year risk of lung cancer were referred for a low dose CT3 scan. RESULTS: A total of 4 566 subjects attended the appointment for risk assessment and 3 591 (79%) consented to data sharing. More than 80% of the patients were in the most deprived quintile of the index of multiple deprivation. Of those attending, 63% underwent spirometry and 43% were recommended for a CT scan. A total of 25 cancers were diagnosed, of which 16 (64%) were stage I. Comparison with the national stage distribution implied that the programme was reducing lung cancer mortality by 22%. CONCLUSIONS: Community based proactive approaches to early diagnosis of lung cancer in health deprived regions are likely to be effective in early detection of lung cancer.en_US
dc.description.sponsorshipLiverpool Clinical Commissioning Groupen_US
dc.format.extent66 - 71en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofLung Canceren_US
dc.rights© 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectEarly diagnosisen_US
dc.subjectHealth inequalitiesen_US
dc.subjectLow-dose CTen_US
dc.subjectLung canceren_US
dc.subjectSmokingen_US
dc.titleEvaluation of a health service adopting proactive approach to reduce high risk of lung cancer: The Liverpool Healthy Lung Programme.en_US
dc.typeArticle
dc.identifier.doi10.1016/j.lungcan.2019.05.026en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/31319997en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume134en_US
dcterms.dateAccepted2019-05-26en_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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