Browsing Queen Mary University of London Theses by Subject "invasive breast cancer"
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Relationship between altered myoepithelial phenotype and the inflammatory cell infiltrate in progression of DCIS
(Queen Mary University of London, 2015-08-01)Changes in the microenvironment have been implicated in the transition of pre-invasive ductal carcinoma in-situ (DCIS) to invasive breast cancer. Normal myoepithelial cells have a tumour suppressor phenotype but they are ... -
The role of P13K p1168 in the regulation of gene expression in murine macrophages.
(Queen Mary University of London, 2012)PI3K are a family of lipid kinase enzymes that are involved in a broad spectrum of cellular, physiological and pathological processes. Notably, PI3K dysfunction is associated with cancer, inflammation and metabolism. The ...