Browsing Queen Mary University of London Theses by Subject "Magnetron"
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Investigating cancer-like DNA methylation patterns and genome stability upon reprogramming to naïve human pluripotency
(Queen Mary University of London, 16/09/2019)Aberrant DNA hypermethylation of promoter CpG islands in the context of a hypomethylated genome is a hallmark of cancer. DNA hypomethylation is typically associated with genomic instability while CpG island hypermethylation ...