Browsing Queen Mary University of London Theses by Subject "Joints"
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Bone loss in osteoporosis and rheumatoid arthritis diseases: The effects of disease mechanisms, age, gender and ethnic origin on responsiveness to treatment.
(Queen Mary University of London, 2014-08)Bone makes up a framework that provides protection for internal body organs. The homeostasis of bone is maintained by a balanced process involving old bone degradation and new bone formation. However, this balance can be ... -
Development of a latent IL-17 antagonist for targeted therapy of rheumatoid arthritis.
(Queen Mary University of London, 2012-11)Cytokine based therapies can be targeted to the sites of active inflammation by modifying a given cytokine as a LAP-cytokine. IL-17A has been shown to directly contribute to pathogenesis of rheumatoid arthritis (RA). IL-17F, ...