Browsing Queen Mary University of London Theses by Subject "Hypertension"
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Functional characterization of solute carrier family 39 member 8 variant in relation to hypertension and coronary artery disease.
(Queen Mary University of London, 2015-12-03)Hypertension and coronary artery disease are complex diseases with both environmental and genetic contributions. Genome-wide association studies (GWASs) have revealed a number of common genetic variants with modest effects ... -
The Impact of the Blood Pressure- Associated Genetic Locus at SLC4A7 on Gene Expression and Intracellular pH Regulation
(Queen Mary University of London, 2017-02-23)Genome-wide association studies have revealed an association between variation at the SLC4A7 locus and blood pressure. SLC4A7 encodes the electroneutral Na+/HCO3 – co-transporter NBCn1 which regulates intracellular pH ... -
The impact, assessment, and longitudinal course of negative symptoms of schizophrenia.
(Queen Mary University of London, 23/11/2016)The negative symptoms of schizophrenia include impoverished speech, affective blunting, an inability to anticipate pleasure, asociality, and amotivation. Current effective treatment options are limited, which is a ...