Browsing Queen Mary University of London Theses by Subject "Adenomatous polyposis coli"
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Targeting APC loss using synthetic lethality in Colorectal Cancer
(Queen Mary University of London, 2018-07-23)Mutations in the tumour suppressor gene Adenomatous polyposis coli (APC) are found in 80 % of sporadic colorectal cancer (CRC) tumours and are also responsible for the inherited form of CRC, Familial adenomatous polyposis ...