Browsing Queen Mary University of London Theses by Author "Yuzugulen, Jale"
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Characterisation of Proendothelin-1 Derived Peptides and Evaluation of Their Utility as Biomarkers of Vascular and Renal Pathologies
Yuzugulen, Jale (Queen Mary University of London, 02/06/2014)Endothelin-1 (ET-1), the potent vasoconstrictor peptide, is synthesised from the 212 amino acid precursor preproendothelin-1 (ppET-1). ET-1 is strongly implicated in cardiac and renal pathologies. However, ET receptor ...