Browsing Queen Mary University of London Theses by Author "Rahman, Muhammad Mahmudur"
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Characterisation of a novel in vitro model of Basal cell carcinoma (BCC) through stable PTCH1 suppression in immortalised human keratinocytes
Rahman, Muhammad Mahmudur (Queen Mary University of London, 2013)Basal cell carcinoma (BCC) of the skin is predominantly associated with mutational inactivation of the PTCH1 tumour suppressor gene resulting in constitutive activation of the Hedgehog (HH) developmental pathway. Tumour ...