Browsing Centre for Genomics and Child Health by Subject "Vaccines"
Now showing items 1-3 of 3
-
Causes of impaired oral vaccine efficacy in developing countries.
(2018-01)Oral vaccines are less immunogenic when given to infants in low-income compared with high-income countries, limiting their potential public health impact. Here, we review factors that might contribute to this phenomenon, ... -
Cytokine responses to the anti-schistosome vaccine candidate antigen glutathione-S-transferase vary with host age and are boosted by praziquantel treatment.
(Public Library of Science, 2014-05-08)BACKGROUND: Improved helminth control is required to alleviate the global burden of schistosomiasis and schistosome-associated pathologies. Current control efforts rely on the anti-helminthic drug praziquantel (PZQ), which ... -
Exploring the relationship between environmental enteric dysfunction and oral vaccine responses.
(2018-07)Oral vaccines significantly underperform in low-income countries. One possible contributory factor is environmental enteric dysfunction (EED), a subclinical disorder of small intestinal structure and function among children ...