Browsing Centre for Genomics and Child Health by Subject "5-hydroxymethylcytosine"

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    • Tet3 regulates cellular identity and DNA methylation in neural progenitor cells. 

      Santiago, M; Antunes, C; Guedes, M; Iacovino, M; Kyba, M; Reik, W; Sousa, N; Pinto, L; Branco, MR; Marques, CJ (2019-10-23)
      TET enzymes oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), a process thought to be intermediary in an active DNA demethylation mechanism. Notably, 5hmC is highly abundant in the brain and in neuronal ...